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Nance Lab
Disease-Directed Engineering
Explore peer reviewed reviews, original research, book chapters, software, and collaborative papers from the Nance lab at UW. If you are interested in the foundational research for the Nance lab that was done by Dr. Nance during her PhD and Postdoc, use the dropdown menu to select "Nance PhD & Postdoc" to see these papers! Looking for papers on a specific topic or by a specific author? Click on a tag on the right hand side (or the bottom of the page on the mobile version) to sort by that topic or author.
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Dendrimer-enabled targeted delivery attenuates glutamate excitotoxicity in CP
Zhang F., Zhang Z., Alt J., Kambhampati S.P., Sharma A., Singh S., Nance E., Thomas A.G., Rojas C., Slusher B.S., Kannan R.M.*, Kannan...
Preferential and increased uptake of hydroxyl-terminated PAMAM dendrimers by activated microglia
Alnasser Y., Kambhampti S.P., Nance E., Rajbhandari L., Shrestha S., Venkatesan A., Kannan R.M., Kannan S.* Preferential and increased...
Strategies to enhance the distribution of nanoparticles in the brain
Zhang C., Mastorakos P., Sobral M., Berry S., Song E., Nance E., Eberhard C.G., Hanes J., Suk J.S. Strategies to enhance the distribution...
Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett Syndrome
Nance E., Kambhampati S.P., Smith E.S. Zhang Z., Zhang F., Singh S., Johnston M.V., Kannan R.M., Blue M.E., Kannan S.* Dendrimer-mediated...
Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures glioma
Zhang C., Nance E., Mastorakos P., Chisholm J., Berry S., Eberhart C., Tyler B., Brem H., Suk J.S., Hanes J.* Convection enhanced...
Maternal inflammation results in altered tryptophan metabolism in rabbit placenta and fetal brain
Williams M., Zhang Z., Drewes J., Nance E., Singh S., Kannan S.* Maternal inflammation results in altered tryptophan metabolism in rabbit...
Surface functionality affects the biodistribution of intra-amniotically delivered dendrimers
Zhang F., Nance E., Zhang Z., Jasty V., Mishra M.K., Kambhampati S.P., Burd I., Romero R., Kannan R., Kannan S.* Surface functionality...
Nanoscale effects in dendrimer-mediated targeting of neuroinflammation
Nance E., Zhang F., Mishra M.K., Zhang Z., Kambhampati S.P., Kannan R.M.*, Kannan S.* Nanoscale effects in dendrimer-mediated targeting...
Maternal inflammation leads to impaired glutamate homeostasis in activated microglia
Zhang Z., Bassam B., Thomas AG., Williams M., Liu J., Nance E., Rojas C., Slusher BS., Kannan S.* Maternal inflammation leads to impaired...
Microglial migration & interactions with dendrimer nanoparticles in the presence of neuroinflammatio
Zhang F., Nance E., Alnasser Y., Kannan R., Kannan S.* Microglial migration and interactions with dendrimer nanoparticles are altered in...
Single particle tracking reveals spatial and dynamic organization of the E. coli biofilm matrix
Birjiniuk A., Billings B., Nance E., Hanes J., Ribbeck K., Doyle S.P.* Single particle tracking reveals spatial and dynamic organization...
Systemic dendrimer-drug treatment of ischemia-induced neonatal white matter injury
Nance E., Porambo M., Mishra M.K., Zhang F., Buelow M., Getzenberg R., Johnston M., Kannan R., Fatermi S-A, Kannan S.* Systemic...
Brain penetrating nanoparticles improve paclitaxel efficacy in malignant gliomas
Nance E., Zhang C., Shih T-Y, Xu Q., Schuster B., Hanes J.* Brain penetrating nanoparticles improve paclitaxel efficacy in malignant...
Noninvasive delivery of stealth, brain-penetrating nanoparticles across the BBB using ultrasound
Nance E., Timbie K., Miller W.G., Song J., Louttit C., Klibanov A.L., Shih T-Y, Swaminathan G., Tamargo R.J., Woodworth G., Hanes J.,...
Biodistribution of Fluorescently-labeled Dendrimers in Neonatal Rabbits: Effect of Neuroinflammation
Lesniak W., Mishra M.K., Jyoti A., Balakrishnan B., Zhang F., Nance E., Romero R., Kannan S., Kannan R.* Biodistribution of...
Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo
Xu Q., Boylan N., Suk J., Wang Y-Y, Nance E., Yang J-C, McDonnell P., Cone R., Duh E., Hanes J.* Nanoparticle diffusion in, and...
A dense PEG coating improves penetration of large polymeric nanoparticles within brain tissue
Nance E., Woodworth G., Sailor K., Shih T-Y, Swaminathan G., Xiang D., Eberhart C., Hanes J.* A dense poly(ethylene glycol) coating...
Particulate matter in cigarette smoke increases ciliary axoneme beating through mechanical stimulati
Navarette C., Sisson J., Nance E., Allen-Gipson D., Hanes J., Wyatt T.* J Aerosol. Med. Pulm. Drug Deliv. (2012) Jun; 25(3):159-68. doi:...
Emerging Insights into Barriers to Effective Brain Tumor Therapeutics
Woodworth G.*, Dunn A., Nance E., Hanes J., Brem H. Frontiers NeuroOnc., (2014) 4:126. doi: 10.3389/fonc.2014.00126 Image by Dr. Ian Suk
Emerging concepts in dendrimer nanomedicine: translational aspects
Kannan R., Nance E., Kannan S., Tomalia D.* J Internal Medicine, (2014)276(6): 579-617. doi: 10.1111/joim.12280
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