The Nance Lab

Department of Chemical Engineering
University of Washington
Box 351750
3781 Okanogan Lane NE 
Seattle, WA, 98195-1750

  • Instagram
  • LinkedIn Social Icon
  • Facebook Social Icon

©2017 by Nance Lab. Proudly created with



37. Liao, R., Wood, T.R. & Nance, E.* Superoxide dismutase reduces monosodium glutamate-induced injury in an organotypic whole hemisphere brain slice model of excitotoxicity. J Biol Eng 14, 3 (2020).


36. Curtis C.D.†, McKenna M.†, Pontes H., Toghani D., Choe A., Nance E.* Predicting in situ nanoparticle behavior using multiple particle tracking and artificial neural networks. Nanoscale (2019) Nov 28;11(46):22515-22530. doi: 10.1039/c9nr06327g.

35. Vojtech L., Zhang M. †, Dave V., Levy C., Hughes S.M., Wang R., Calienes F., Prlic M., Nance E., Hladik F. Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses. PLOS ONE (2019) Oct 17;14(10):e0223901. doi: 10.1371/journal.pone.0223901

34. Wood T., Nance E.* Disease-directed engineering for physiology-driven treatment interventions. APL Bioengineering (2019) Oct 23;3(4):040901. doi: 10.1063/1.5117299

33. Nance E.*, McKenna M.† Nanoparticles for Biomedical Applications, Chapter 7: Challenges and Barriers, in press

32. Yellepeddi V, Joseph A.†, Nance E.* Pharmacokinetics of nanotechnology-based formulations in pediatrics, Adv. Drug. Del. Rev. (2019) Nov - Dec;151-152:44-55. doi: 10.1016/j.addr.2019.08.008

31. Zhang M †, Bishop B., Thompson N., Hildahl K.‡, Dang B.‡, Mironchuk O.‡, Chen N. ‡, Aoki R., Holmberg V.,* Nance E.* Systematic evaluation of CdSe-quantum dot toxicity and cellular uptake in the developing brain. Nanoscale advances (2019) 1, 3424-3442. doi: 10.1039/C9NA00334G

30. Nance E.* Careers in nanomedicine and drug delivery. Adv. Drug. Del. Rev. (2019)

29. Millik S.C., Dostie A.M., Karis D.G., Smith P.T., Mckenna M.†, Chan N.†, Curtis C.D.†, Nance E., Theberge A.B., Nelson A. 3D printed coaxial nozzles for extrusion of hydrogel tubes toward modeling vascular endothelium. Biofabrication (2019) Jul 12;11(4):045009. doi: 10.1088/1758-5090/ab2b4d.


28.  Wood T., Maralejo D., Corry K., Snyder J., Traudt C., Curtis C.†, Nance E., Parikh P., Juul S.* A ferret model of encephalopathy of prematurity, Developmental Neuroscience (2018) 40:475-489​

27.  Curtis C.†, Toghani D.‡, Wong B. ‡, Nance E.* Colloidal stability as a determinant of nanoparticle behavior in the brain. Colloids and Surfaces B: Biointerfaces (2018) 170, 673-682. PDF

26.  Joseph A.†, Wood T., Chen C-C.†, Corry K., Juul S., Snyder J., Parikh P., Nance E.* Curcumin-loaded brain penetrating nanoparticles for treatment of neonatal hypoxia-ischemia encephalopathy. Nano Research (2018) 11(10): 5670-5688. PDF

25.  Alnasser Y., Kambhampti S.P., Nance E., Rajbhandari L., Shrestha S., Venkatesan A., Kannan R.M., Kannan S.* Preferential and increased uptake of hydroxyl-terminated PAMAM dendrimers by activated microglia in rabbit brain mixed glial culture. Molecules (2018) 23(5). PDF

24.  Vornhagen J., Armistead B., Quach P., Santana-Ufret V., Boldenow E., Alishetti V., Melief C., Ngo L.Y., Whidbey C., Doran K.S., Curtis C.†, Nance E., Rajagopal L.* Bacteria exploit epithelial exfoliation for ascending infection. J. Clinical Investigation (2018) 15(1):14. *Cover image PDF


23.  Nance E., Kambhampati S.P., Smith E.S. Zhang Z., Zhang F., Singh S., Johnston M.V., Rangaramanujam K., Blue M.E., Kannan S.* Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett Syndrome.  J. Neuroinflammation (2017) 14(1): 252 PDF

22.  Zhang C., Nance E., Mastorakos P., Chisholm J., Berry S., Eberhart C., Tyler B., Brem H., Suk J.S., Hanes J.* Convection Enhanced Delivery of Cisplatin-Loaded Brain Penetrating Nanoparticles Cures Malignant Glioma in Rats. J Control. Release (2017) S0168-3659(17)30110-4 PDF

21.  Williams M., Zhang Z., Drewes J., Nance E., Singh S., Kannan S.* Maternal Inflammation Results in Altered Tryptophan Metabolism in Rabbit Placenta and Fetal Brain. Developmental Neuroscience (2017) 39(5):399-412  PDF

20.  Smith J.*, Sprenger K.*, Liao R.†, Joseph A.†, Nance E.,* Pfaendtner J.* Determining Dominant Driving Forces Affecting Controlled Protein Release from Polymeric Nanoparticles. Biointerphases (2017) 12(2):02D412  PDF

19.  Zhang C., Mastorakos P., Sobral M., Berry S., Song E., Nance E., Eberhard C.G., Hanes J., Suk J.S. Strategies to enhance the distribution of nanoparticles in the brain. J. Control Release (2017) 267:232-239  PDF

18.  Nance E.* Brain penetrating nanoparticles for analysis of the brain microenvironment. Methods Mol. Biol. (2017) 1570:91-104 PDF


17.  Curtis C.†, Zhang M.†, Liao R.†, Wood T.†, Nance E.* Systems-level thinking for nanoparticle-mediated therapeutic delivery to neurological diseases. Wiley Interdiscip Rev Nanomed Nanobiotechnol. (2016) **selected cover image: Curtis, C., Zhang, M., Liao, R., Wood, T. and Nance, E. Cover Image, Volume 9, Issue 2. WIREs Nanomed Nanobiotechnol, (2017) 9: n/a, e1463. doi:10.1002/wnan.1463​  PDF

16.  Zhang F., Nance E., Zhang Z., Jasty V., Mishra M.K., Kambhampati S.P., Burd I., Romero R., Kannan R., Kannan S.* Surface functionality affects the biodistribution and microglia-targeting of intra-amniotically delivered dendrimers. J Control. Release, (2016) 237:61-70 PDF

15.  Nance E., Zhang F., Mishra M.K., Zhang Z., Kambhampati S.P., Kannan R.*, Kannan S.* Nanoscale effects in dendrimer-mediated targeting of neuroinflammation. Biomaterials (2016) 101:96-107 PDF

14.  Zhang Z., Bassam B., Thomas AG., Williams M., Liu J., Nance E., Rojas C., Slusher BS., Kannan S.* Maternal inflammation leads to impaired glutamate homeostatis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain. Neurobiol. Dis. (2016) S0969-9961(16)30143-7​ PDF

13.  Zhang F., Nance E., Alnasser Y., Kannan R., Kannan S.* Microglia migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. J Neuroinflammation (2016) 13(1):65  PDF


12.  Nance E., Porambo M., Mishra M.K., Zhang F., Buelow M., Getzenberg R., Johnston M., Kannan R., Fatermi S-A, Kannan S.* Systemic dendrimer-drug treatment of ischemia-induced neonatal white matter injury. J Control. Release, (2015) 214: 112-120 PDF


11.  Nance E., Zhang C., Shih T-Y, Xu Q., Schuster B., Hanes J.* Brain penetrating nanoparticles improve paclitaxel efficacy in malignant gliomas following local administration. ACS Nano (2014) 8(10):10655-10664 PDF

10.  Nance E., Timbie K., Miller W.G., Song J., Louttit C., Klibanov A.L., Shih T-Y, Swaminathan G., Tamargo R.J., Woodworth G., Hanes J., Price R.J.* Noninvasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound. J Control. Release, (2014) 189:123-132. **Controlled Release Society award for best paper of the year PDF

9.  Woodworth G.*, Dunn A., Nance E., Hanes J., Brem H. Emerging Insights into Barriers to Effective Brain Tumor Therapeutics. Frontiers NeuroOnc., (2014) 4:126 PDF

8.  Birjiniuk A., Billings B., Nance E., Hanes J., Ribbeck K., Doyle S.P.* Single particle tracking reveals spatial and dynamic organization of the E. coli biofilm matrix. New J Physics (2014) 16(8): 085014 PDF

7.  Kannan R., Nance E., Kannan S., Tomalia D.* Emerging concepts in dendrimer nanomedicine: translational aspects. J Internal Medicine, (2014) 276(6): 579-617 PDF


6.  Balakrishnan B., Nance E., Johnston M., Kannan S.* Nanotechnology in cerebral palsy: current developments. Int. J Nanomedicine (2013) 8:4183-4195. PDF

5.  Lesniak W., Mishra M.K., Jyoti A., Balakrishnan B., Zhang F., Nance E., Romero R., Kannan S., Kannan R.* Biodistribution of Fluorescently-labeled PAMAM Dendrimers in Neonatal Rabbits: Effect of Neuroinflammation. Mol. Pharmaceutics (2013) 8(10):e77164PDF

4.  Xu Q., Boylan N., Suk J., Wang Y-Y, Nance E., Yang J-C, McDonnell P., Cone R., Duh E., Hanes J.* Nanoparticle movement through bovine vitreous gel ex vivo. J Control Release. (2013) 167(1), 76-84. **Selected Cover Image PDF


3.  Nance E., Woodworth G., Sailor K., Shih T-Y, Swaminathan G., Xiang D., Eberhart C., Hanes J.* A dense poly(ethylene glycol) coating improves penetration of large  polymeric nanoparticles within brain tissue. Sci. Transl. Med. (2012) 4, 149ra119. **Selected Cover Image PDF

2.  Navarette C., Sisson J., Nance E., Allen-Gipson D., Hanes J., Wyatt T.* Particulate matter in cigarette smoke increases ciliary axoneme beating through mechanical stimulation. J Aerosol. Med. Pulm. Drug Deliv. (2012) 25(3):159-68 PDF

1.  Montero C., Lewis D., Johnson M., Conners S., Nance E., Nichols J., Kelly R.* Colocation of genes encoding a tRNA-mRNA hybrid and a putative signaling peptide on complimentary strands in the genome of the hyperthermophilic bacterium Thermotoga maritima. J Bacteriol. (2006) 19, 6802-6807 PDF


  1. Nance E. Clinical agitation prevents sperm agglutination. Sci. Transl. Med. Editor’s Choice (2018); 11 (478), eaaw5323.

  2. Nance E. Magnets make target cells more attractive to CRISP. Sci. Transl. Med. Editor’s Choice (2018); 10(470), eaaw0520.

  3. Nance E. Predicting pathology provides prostate prognostication. Sci. Transl. Med. Editor’s Choice (2018); 10(462), eaav3886.

  4. Nance E. Platelets prefer to be shaken, not stirred. Sci. Transl. Med. Editor’s Choice (2018), 10(454), eaau7388.

  5. Nance E. Ketogenic bugs as epileptic drugs. Sci Transl. Med. Editor’s Choice (2018), 10(446), eaau0471.

  6. Nance E. Nano livers: A sobering Discovery. Sci Transl. Med. Editor’s Choice (2018), 10(438), eaat4479.

  7. Nance E. GO minions – polarize and repair! Sci. Transl. Med Editor’s Choice (2018), 10(430), eeas8967.


For bibliography and citation information for Elizabeth Nance, please check out the following links:

My Bibliography

Google Scholar